Current principles of use of topical hemostatic agents in trauma cases
Mehmet Eryılmaz1, Öner Menteş2, M. Tahir Özer2, Gürkan Ersoy3, Murat Durusu4, Ülkümen Rodoplu5, Serkan Bilgiç1, Murat Kalemoğlu6, Ali ihsan Uzar2, Köksal Öner1
1Gülhane Askeri Tıp Akademisi, Acil Tıp Anabilim Dalı, Ankara
2Gülhane Askeri Tıp Akademisi, Genel Cerrahi Anabilim Dalı, Ankara
3Dokuz Eylül Üniversitesi Tıp Fakültesi, Acil Tıp Anabilim Dalı, İzmir
4Diyarbakır Asker Hastanesi Acil Servis, Diyarbakır
5Alsancak Devlet Hastanesi Acil Servisi, İzmir
6Gata Haydarpaşa Eğitim Hastanesi, Acil Servisi İstanbul.
Abstract
Hemorrhage is the most common cause of preventable deaths both in civilian and military trauma. Simple hemorrhage control and tourniquets can be applied in extremity injuries but hemostasis in the axillary and femoral region is rather challenging. In this study, results on the efficacy of topical hemostatic agents in post-traumatic hemorrhages reported in the literature are reviewed. As conclusion, current information on topical hemostatic agents depend upon a few case reports, data from mostly experimental studies and subjective evaluations in the field, but there are no prospective, randomized studies with control group. Evaluations regarding the use of topical hemostatic agents to reduce the mortality need to be supported by studies with higher level of evidence