Aydan Mutis Alan1*, Ozkan Alan2

1Departments of Internal Medicine, Tekirdag State Hospital, Tekirdag, Turkey
2Departments of Medical Oncology, Tekirdag State Hospital, Tekirdag, Turkey

Keywords: Acute renal failure, emergency treatment, hyperuricemia, small-cell lung carcinoma, tumor lysis syndrome


Tumor lysis syndrome (TLS) is an oncologic emergency. It generally occurs after chemotherapy but sometimes develops spontaneously in hematologic malignancy, such as leukemia. TLS is a rare phenomenon in patients with solid tumors, particularly when it develops spontaneously. Here, we present a case of spontaneous TLS (STLS) in a patient with small-cell lung cancer (SCLC). We report a case of STLS in a 59-year-old male patient who presented with dyspnea and oliguria. Clinicians should suspect TLS in patients with malignancy, who demonstrate the classic electrolyte abnormalities of TLS even if not receiving treatment such as chemotherapy or radiotherapy.

How to cite this article: Alan AM, Alan O. A case of spontaneous tumor lysis syndrome in extensive-stage small-cell lung cancer: A rare oncologic emergency. Turk J Emerg Med 2020;20:142-5.

Author Contributions

AMA contributed to clinical management of the case, manuscript editing, final approval, and corresponding author. OA contributed to the evaluation of patients’ follow-up, design of the writing, and support of the literature.

Conflict of Interest

None declared.

Financial Disclosure

None declared.