The Analysis of Escherichia Coli Resistance in Urine Culture and in Antibiograms as Requested by Emergency Service

Yavuz YIGIT; Vesile YAZICI; Harun AYHAN; Emin Gokhan GENCER; Huseyin Cahit HALHALLI; Onur KARAKAYALI; Yahya Kemal GUNAYDIN

doi:10.5505/1304.7361.2014.09068

Yavuz YIGIT¹, Vesile YAZICI², Harun AYHAN³, Emin Gokhan GENCER⁴, Huseyin Cahit HALHALLI¹, Onur KARAKAYALI¹, Yahya Kemal GUNAYDIN⁵

¹Department of Emergency, Derince Training and Research Hospital, Kocaeli
²Department of Microbiology, Derince Training and Research Hospital, Kocaeli
³Department of Emergency, Haydarpasa Training and Research Hospital, Istanbul
⁴Department of Emergency, Dr. Lutfi Kirdar Kartal Training and Research Hospital, Istanbul
⁵Department of Emergency, Konya Training and Research Hospital, Konya

Keywords: Culture; E. coli; emergency; urine

Abstract

Objectives

The aim of this study was to determine the antibiotic resistance of infectious and non-infectious E. coli species in order to increase the success of empirical antibiotic treatment in urinary system infections.

Methods

The antibiotic susceptibility of 464 E. coli strains that were isolated from urine samples of patients who visited Derince Training and Research Hospital Emergency Department between January 1 and December 31, 2012 were retrospectively evaluated from records. The antibiogram results were classified as susceptible, moderately susceptible or resistant. Moderately susceptible strains were assumed to be resistant.

Results

Bacterial proliferation was seen in 563 (28.1%) of the 1998 urine cultures tested. One hundred and twelve cultures could not be evaluated due to contamination, and there was no proliferation in 1323 cultures. E. coli strains were isolated in 464 (82.4%) of the cultures in which proliferation was seen. Three hundred and sixty seven (79%) of the patients were female, 97 (21%) were male, and the mean age of all of the patients was 41.1±24.1 years (min: 1, max: 90). The antibiograms of the E. coli strains revealed that meropenem had the lowest resistance (0%), while ampicillin-sulbactam had the highest resistance (36.8%).

Conclusions

In this study, we investigated the antibiotic resistance of E. coli strains isolated from urine cultures in our region. Future studies, perhaps similar to this one, can be performed in the future to increase the success of treatments.