Analyzes of urine cultures and antibiograms ordered from emergency department

Abstract

Objectives: Urinary tract infections (UTI) are come upon a common infection disease in emergency department (ED). Urine culture is gold standards to diagnosis and antibiograms are useful to continuation of treatment. Empiric antibiotic therapy begins patients who suspected UTI because obtaining antibiogram result is time consuming. Treatment success depends on causative microorganism and antibiotic choice. Aim of the study was investigate to urine culture and antibiogram results to adult patients who admitted to ED.
Materials and Methods: Urine cultures were investigated that ordered from ED between January and June 2006 in database of laboratory information system. Samples of isolated microorganism and antibiogram results were evaluated.
Results: Microorganisms were isolated in 90 of 257 urine cultures. Polymicrobial infection was determined in six patients. Mean age was 48.04±17.9 (18-83) of 84 patients. Sixty patients (%71.4) were female. Most common identificated microorganism was E. coli (52 samples, %57.8) in urine cultures. If all samples considered, bacterial resistance was detected against to ampicilline, trimethoprim/sulfamethoxazole (TMP/SMX) ampicilline/sulbactam (AMS) and ciproşoxacin (CIP) (64.7%, 43.7%, 41.3% and 37.6%, respectively). Lower bacterial resistance was determined against to amikacin, gentamicine, tobramicine and nitrofurantoin (3.6%, 13.3%, 14.5% and 17.6%, respectively). E. coli isolated samples were investigated, bacterial resistance was detected against to ampicilline, CIP, levoşoxacin and TMP/SMX (64%, 48%, 47.1% and 40.4%, respectively). Nitrofurantoin, amikacin, gentamicine and tobramicine were found as sensitive antibiotics (85.3%, 85%, 82.4% and 76.9%, respectively).
Conclusion: High bacterial resistance was determined against to most preferred empiric antibiotics that TMP/SMX, AMS and also CIP. Our opinion, empiric antibiotic choice would revise for UTI patients.